Int. J. of Bioinformatics Research and Applications   »   2005 Vol.1, No.1



Title: Mining and analysing scale-free protein–protein interaction network


Author: Xiaohua Hu


Address: College of Information Science and Technology, Drexel University, Philadelphia, PA 19104, USA


Abstract: Protein–protein interaction network is essential to understand the fundamental processes that govern cell biology. In this paper, we integrate information extraction and data mining techniques to extract and mine the scale-free protein–protein interaction network from biomedical literature. The experiments on around 1,600 chromatin proteins indicate that our system is very promising for mining and analysing protein–protein interaction network.


Keywords: scale-free network graph; protein–protein interaction; biomedical literature; data mining; clustering; chromatin proteins; information extraction; information retrieval; bioinformatics; computational biology.


DOI: 10.1504/IJBRA.2005.006904


Int. J. of Bioinformatics Research and Applications, 2005 Vol.1, No.1, pp.81 - 101


Available online: 21 Apr 2005



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