Int. J. of Nanomanufacturing   »   2014 Vol.10, No.4

 

 

Title: Experimental research on cell configuration control with micro-fluid

 

Authors: Qin Zhang; Weijun Huang; Wuchen Lei; Gang Su; Hisayuki Aoyama

 

Addresses:
School of Mechanical and Automotive Engineering, South China University of Technology, Tianhe District, Guangzhou 510641, China
School of Mechanical and Automotive Engineering, South China University of Technology, Tianhe District, Guangzhou 510641, China
School of Mechanical and Automotive Engineering, South China University of Technology, Tianhe District, Guangzhou 510641, China
School of Mechanical and Automotive Engineering, South China University of Technology, Tianhe District, Guangzhou 510641, China
Department of Mechanical Engineering and Intelligent Systems, University of Electro-Communications, Chofu, Tokyo 182-8585, Japan

 

Abstract: Configuration (position and orientation) control is an important issue in the micromanipulation of cells. A non-contact method based on micro-fluid for cell configuration control is presented in this paper. A cell is positioned by the balanced pressure of a pair of lined micro-fluids from two tiny tubes. The orientation control is achieved by rotating the cell in a swirl caused by a pair of parallel opposite micro-fluids from the two tubes. With fluctuant micro-fluids generated by pulsating jetting, cell orientation can be controlled more precisely. The method is valid for cells of different shapes and sizes. The effectiveness of the proposed non-contact method for cell configuration control was verified by experiments.

 

Keywords: cell micromanipulation; microfluids; cell configuration control; swirl; pulsating jetting; non-contact; orientation control; cells.

 

DOI: 10.1504/IJNM.2014.062976

 

Int. J. of Nanomanufacturing, 2014 Vol.10, No.4, pp.358 - 370

 

Available online: 27 Jun 2014

 

 

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