Title: Effects of metallic and metal oxide nanoparticles in aquatic and terrestrial food chains. Biomarkers responses in invertebrates and bacteria

Authors: A. Thiéry; L. De Jong; J. Issartel; X. Moreau; G. Saez; P. Barthélémy; I. Bestel; C. Santaella; W. Achouak; M. Auffan; J. Rose; J-Y. Bottero

Addresses: UMR-CNRS/IRD 6116/GDRi iCEINT (CNRS-CEA), Institut Méditerranéen d'Ecologie et de Paléoécologie, équipe 'Biomarqueurs et Bioindicateurs Environnementaux', Département Organisation et Vulnérabilité des Systèmes Ecologiques, Aix-Marseille Université, 3 place Victor Hugo, Case 97, 13331 Marseille Cedex 3, France. ' UMR-CNRS/IRD 6116/GDRi iCEINT (CNRS-CEA), Institut Méditerranéen d'Ecologie et de Paléoécologie, équipe 'Biomarqueurs et Bioindicateurs Environnementaux', Département Organisation et Vulnérabilité des Systèmes Ecologiques, Aix-Marseille Université, 3 place Victor Hugo, Case 97, 13331 Marseille Cedex 3, France. ' UMR-CNRS/IRD 6116/GDRi iCEINT (CNRS-CEA), Institut Méditerranéen d'Ecologie et de Paléoécologie, équipe 'Biomarqueurs et Bioindicateurs Environnementaux', Département Organisation et Vulnérabilité des Systèmes Ecologiques, Aix-Marseille Université, 3 place Victor Hugo, Case 97, 13331 Marseille Cedex 3, France. ' UMR-CNRS/IRD 6116/GDRi iCEINT (CNRS-CEA), Institut Méditerranéen d'Ecologie et de Paléoécologie, équipe 'Biomarqueurs et Bioindicateurs Environnementaux', Département Organisation et Vulnérabilité des Systèmes Ecologiques, Aix-Marseille Université, 3 place Victor Hugo, Case 97, 13331 Marseille Cedex 3, France. ' UMR-CNRS/IRD 6116/GDRi iCEINT (CNRS-CEA), Institut Méditerranéen d'Ecologie et de Paléoécologie, équipe 'Biomarqueurs et Bioindicateurs Environnementaux', Département Organisation et Vulnérabilité des Systèmes Ecologiques, Aix-Marseille Université, 3 place Victor Hugo, Case 97, 13331 Marseille Cedex 3, France. ' INSERM, U869, Univ. Bordeaux, ARNA Laboratory, 33000 Bordeaux, France. ' INSERM, U869, Univ. Bordeaux, ARNA Laboratory, 33000 Bordeaux, France. ' UMR 6191 CNRS-CEA-Aix-Marseille University/GDRi iCEINT (CNRS-CEA), LEMIRE Laboratory of Microbial Ecology and Extreme Environments, CEA Cadarache, 13108 Saint-Paul-Lez-Durance, France. ' UMR 6191 CNRS-CEA-Aix-Marseille University/GDRi iCEINT (CNRS-CEA), LEMIRE Laboratory of Microbial Ecology and Extreme Environments, CEA Cadarache, 13108 Saint-Paul-Lez-Durance, France. ' CNRS, CEREGE, UMR 6635, 13545 Aix en Provence, France; GDRi iCEINT internationnal Consortium for the Environmental Implications of NanoTechnology (CNRS-CEA), Aix-Marseille Univ, CEREGE, UMR 6635, 13545 Aix-en-Provence, France. ' CNRS, CEREGE, UMR 6635, 13545 Aix en Provence, France; GDRi iCEINT internationnal Consortium for the Environmental Implications of NanoTechnology (CNRS-CEA), Aix-Marseille Univ, CEREGE, UMR 6635, 13545 Aix-en-Provence, France. ' CNRS, CEREGE, UMR 6635, 13545 Aix en Provence, France; GDRi iCEINT internationnal Consortium for the Environmental Implications of NanoTechnology (CNRS-CEA), Aix-Marseille Univ, CEREGE, UMR 6635, 13545 Aix-en-Provence, France

Abstract: Although the market of nanoparticles (NPs) is rapidly expanding, the environmental and health impact of manufactured NPs and nanomaterials is still poorly understood and predictable. Hence, several laboratories of the PACA region have unified their skills to address this issue with an interdisciplinary approach. We present an outline of the ecological impact of metallic and metal oxide NPs span from the surface atoms of NPs, to unicellular organisms, such as bacteria, and organism levels. On multicellular organisms, we focus on biomarkers reporting on stress, central nervous system endpoints and antioxidative balance assessment. On bacteria, which are key players in NPs transfer, we study not only the impact of NPs on cells, at the microbial community, cell and molecular level, but also the effect of cells on NPs. Our priority is through our collaborations, to surpass case-by-case studies and develop aquatic and terrestrial mesocosms, to get information at an integrative level on the trophic links and ecosystemic consequences of NPs.

Keywords: aquatic food chain; terrestrial food chain; biomarkers; invertebrates; bacteria; metal oxide nanoparticles; mesocosms; biofilm; surface reactivity; biotransformation; nanotechnology; environmental impact; health impact; nanomaterials; trophic links; ecosystems.

DOI: 10.1504/IJNT.2012.045326

International Journal of Nanotechnology, 2012 Vol.9 No.3/4/5/6/7, pp.181 - 203

Published online: 06 Feb 2012 *

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