Title: Impulse response and Modulation Transfer Function analysis for Shift-And-Add and Back Projection image reconstruction algorithms in Digital Breast Tomosynthesis (DBT)

Authors: Ying Chen, Joseph Y. Lo, James T. Dobbins III

Addresses: Department of Electrical and Computer Engineering, Biomedical Engineering Graduate Program, Southern Illinois University, Carbondale IL 62901, USA; Duke Advanced Imaging Laboratories, Department of Biomedical Engineering, Duke University, Durham NC 27705, USA. ' Duke Advanced Imaging Laboratories, Department of Biomedical Engineering and Radiology, Medical Physics Graduate Program, Duke University, Durham NC 27705, USA. ' Duke Advanced Imaging Laboratories, Department of Biomedical Engineering and Radiology, Medical Physics Graduate Program, Duke University, Durham NC 27705, USA

Abstract: Breast cancer is second only to lung cancer as the leading cause of non-preventable cancer death in women. Digital Breast Tomosynthesis (DBT) is a promising technique to improve early breast cancer detection. In this paper, we present the impulse response and Modulation Transfer Function (MTF) analysis to quantitatively compare Shift-And-Add (SAA) and point-by-point Back Projection (BP) three-dimensional image reconstruction algorithms in DBT. A Filtered Back Projection (FBP) deblurring algorithm based on point-by-point BP was used to demonstrate deblurred tomosynthesis images.

Keywords: mammography; image reconstruction; digital breast tomosynthesis; DBT; shift-and-add; SAA; back projection; filtered back projection; FBP; impulse response; modulation transfer function; MTF; breast cancer; cancer detection; early detection; deblurred images.

DOI: 10.1504/IJFIPM.2008.020187

International Journal of Functional Informatics and Personalised Medicine, 2008 Vol.1 No.2, pp.189 - 204

Published online: 08 Sep 2008 *

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