Text mining and visualisation of Protein-Protein Interactions Online publication date: Sat, 24-Jan-2015
by Flora S. Tsai
International Journal of Computational Biology and Drug Design (IJCBDD), Vol. 4, No. 3, 2011
Abstract: The study of Protein-Protein Interactions (PPIs) is of great importance in determining the biological function and impact of proteins. However, the constant discovery of new PPIs makes it extremely time-consuming to manually extract information from new publications. In addition, it is necessary to view and simulate protein interactions in three dimensions. This paper presents a text mining and visualisation framework for finding details of PPIs that occur within a particular subcellular location. By obtaining the sequence of the amino acids at the interface of a protein interaction, one can obtain a deeper understanding about the function of the protein.
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