Normalised compression distance and evolutionary distance of genomic sequences: comparison of clustering results
by Massimo La Rosa, Salvatore Gaglio, Riccardo Rizzo, Alfonso Urso
International Journal of Knowledge Engineering and Soft Data Paradigms (IJKESDP), Vol. 1, No. 4, 2009

Abstract: Genomic sequences are usually compared using evolutionary distance, a procedure that implies the alignment of the sequences. Alignment of long sequences is a time consuming procedure and the obtained dissimilarity results is not a metric. Recently, the normalised compression distance was introduced as a method to calculate the distance between two generic digital objects and it seems a suitable way to compare genomic strings. In this paper, the clustering and the non-linear mapping obtained using the evolutionary distance and the compression distance are compared, in order to understand if the two distances sets are similar.

Online publication date: Mon, 19-Oct-2009

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